Carotenoids are natural pigments attracting attention of physicists, chemists and biologists due to their multiple functions in the nature. While carotenoids have unusually high extinction coefficients, they do not exhibit adequate emission. This fact has resulted in detailed studies of photophysical and photochemical properties of carotenoids and their role as light-harvesting pigments in photosynthesis.
Modulating The Morbidity of Inflammation
Inflammation is a necessary and critical component of the healing system and the overall actions of the immune system. The immune system is an integrated network of organs and cells that protect the host from invasion and modulate reaction once invasion has occurred. The immune system depends on self-regulation to dampen the potential for unrelenting self -destruction of autoimmune reactions. The balance in the system (immunomodulation ) is critical to the overall health of the immune system and thus the human system. Acute inflammation is modulated by the immune system to take care of an immediate problem…then it is supposed to shut itself off. Chronic inflammation is an issue that is a representation of the immune system out of control…an immune system that does not shut itself off. The immune (inflammatory) system then becomes a smoldering fire that creates significant issues throughout the bodily systems including the eye. Chronic inflammation is responsible for destabilizing cholesterol deposits (heart attack and stroke), destroying nerve cells (dementias), proliferating abnormal cells and potentially transforming them to cancer, and impacting on devastating disorders of the eye such as macular degeneration, uveitis and glaucoma.
Constant light conditions (LL) carry a risk of disrupting the biological clock of developing animals. Our purpose in this study was to investigate what disorders occur in animals receiving an LL stress during the late embryonic and suckling periods as compared with animals housed in dark-light (14 h-10 h) conditions (DL). In addition, we examined ameliorating effects against the disorder by the oral administration of lutein as an antioxidant. LL caused hypertrophy of the spleen and induced a higher expression of serotonin transporter (5HTT) in the corpus striatum and hippocampus in 15-day-old pups.
Let's stop torturing our patients
Traditionally dilating the eyes takes anywhere from 4-12 hours to go away (depending on several factors). That's a long time during today's busy lifestyles. It causes a lot of patients to either outright refuse dilation or begrudingly acecpt the drops all while complaining about the side effects.
With a new mixture of anti-dilation drops, we can reduce that time down to 45 minutes. If we can get more people dilated we can find more pathology, save our patient's vision, and generally be better doctors by caring about their daily lives.Wednesday, 02 October 2013 Written by Adam Parker, OD Posted in Philosophy/Editorials
Controversy abounds in the arena of the impact of behavior and nutrition related to all disease…including glaucoma. The following is an exercise in science to attempt to bring some organization and sense to the discussion.